Sequence complementarity between human noncoding RNAs and SARS-CoV-2 genes: What are the implications for human health?

Rossella Talotta,Shervin Bahrami,Magdalena Janina Laska

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease（2022）

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摘要

•Viruses may establish an epigenetic crosstalk with human ncRNAs.•SARS-CoV-2 genes overlap with the transcripts of 130 human lncRNAs and 2 snRNAs.•Detected human ncRNAs may be involved in cancer and autoimmune pathways.•Such a nucleotide interaction may be at the basis of COVID-19 complications.

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关键词

SARS-CoV-2,COVID-19,Long non-coding RNA,Small nuclear RNA,Epigenetics,Bioinformatics

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