Frontal fibrosing alopecia: a retrospective clinical review of 58 Egyptian patients with treatment outcome and long-term follow-up

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY(2022)

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摘要
For the first time in 1994, Kossard described a new member of the scarring alopecia disorders wich is called frontal fibrosing alopecia (FFA) (1). It affects post-menopausal females mainly (1, 2). But it may affect premenopausal females (3) and men (4). Some dermatologists consider FFA as a clinical variant of another disorder called lichen planopilaris (LPP), as both show similair histological character (2, 5) but with higher apoptotic activity and less inflammation in FFA. Regarding its behavior and clinical presentations; it shows variations of either slow, rapid, or self-limiting progression (6). Now, its incidence has been markedly increasing (7). Besides, the exact etiology is still unknown, thus, the exact tretment regimen has not been identified. However, several reports found different responses (either improvement or stabilization) on regimens containing topical and intralesional steroids, topical and oral immunomodulators, hydroxychloroquine, and antibiotics (8-10).
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关键词
frontal fibrosing alopecia,lichen planopilaris
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