Cancer-associated fibroblasts-derived exosomes promote lung cancer progression by OIP5-AS1/ miR-142-5p/ PD-L1 axis

Yun Jiang,Kun Wang,Xiaoning Lu,Yongliang Wang,Jianle Chen

Molecular Immunology（2021）

引用 25|浏览5

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摘要

•CAFs suppress the killing effect of PBMCs on lung cancer cells through PD-L1.•Exosomes derived from CAFs suppress the killing effect of PBMCs on lung cancer cells.•MiR-142-5p suppresses lung cancer development through regulating PD-L1 in vivo.

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关键词

Cancer-associated fibroblasts,PBMCs,Lung cancer,PD-L1,OIP5-AS1,miR-142-5p

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