Patterns of leukocyte recovery predict infectious complications after CD19 CAR-T cell therapy in a real-world setting.

Stem cell investigation（2021）

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摘要

Although CAR-T cell therapy is highly effective, infectious complications remain an important cause of morbidity and mortality. Low ANC/ALC and AMC/ALC ratios at D30 are potential novel predictors of infection and can be considered in future prophylactic strategies.

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Chimeric antigen receptor T cell (CAR-T) CD19 cells,axicabtagene ciloleucel,infection,real-world cohort,relapsed/refractory diffuse large B-cell lymphoma (DLBCL)

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