Aquaporin-4 Autoantibody Detection by ELISA: A Retrospective Characterization of a Commonly Used Assay.

Jon P Williams,Justin R Abbatemarco,Jonathan J Galli,Stefanie J Rodenbeck,Lisa K Peterson,Thomas R Haven, Meagan Street,John W Rose,John E Greenlee,M Mateo Paz Soldan,Stacey L Clardy

Multiple sclerosis international（2021）

引用 7|浏览7

暂无评分

摘要

Our data illustrates diagnostic uncertainty associated with the AQP4 ELISA, an assay that is still commonly ordered by clinicians despite the availability of more sensitive and specific tests to detect AQP4 autoantibodies in patients suspected of having NMOSD. In particular, low positive titer AQP4 ELISA results are particularly nonspecific for the diagnosis of NMOSD. The importance of accessibility to both sensitive and specific AQP4 testing cannot be overemphasized in clinical practice.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要