Incorporation of green emission polymer dots into pyropheophorbide-α enhance the PDT effect and biocompatibility

Photodiagnosis and Photodynamic Therapy(2022)

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摘要
•Photodynamic therapy (PDT) is used for the treatment of cancer.•Incorporation of polymer dots into pyropheophorbide-a (PPa) improves the laser induced effects of PPa.•The conjugated drug inherits the pH sensitivity of polymer dots.•The nano-dugs synthesized through different methods possess good biocompatibility and low toxicity.
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关键词
Photodynamic therapy,Up-conversion photoluminescence,Carbon based polymer dots (CPDs),pH sensitivity,Photosensitizers
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