Coded Shotgun Sequencing
IEEE Journal on Selected Areas in Information Theory(2022)
摘要
Most DNA sequencing technologies are based on the shotgun paradigm: many short reads are obtained from random unknown locations in the DNA sequence. A fundamental question, in Motahari et al., (2013), is what read length and coverage depth (i.e., the total number of reads) are needed to guarantee reliable sequence reconstruction. Motivated by DNA-based storage, we study the coded version of...
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关键词
DNA,Sequential analysis,Genomics,Bioinformatics,Reliability,Encoding,Decoding
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