Sample Preparation and Diagnostic Methods for a Variety of Settings: A Comprehensive Review

Zach E. Nichols,Chris D. Geddes

MOLECULES(2021)

引用 0|浏览0
暂无评分
摘要
Sample preparation is an essential step for nearly every type of biochemical analysis in use today. Among the most important of these analyses is the diagnosis of diseases, since their treatment may rely greatly on time and, in the case of infectious diseases, containing their spread within a population to prevent outbreaks. To address this, many different methods have been developed for use in the wide variety of settings for which they are needed. In this work, we have reviewed the literature and report on a broad range of methods that have been developed in recent years and their applications to point-of-care (POC), high-throughput screening, and low-resource and traditional clinical settings for diagnosis, including some of those that were developed in response to the coronavirus disease 2019 (COVID-19) pandemic. In addition to covering alternative approaches and improvements to traditional sample preparation techniques such as extractions and separations, techniques that have been developed with focuses on integration with smart devices, laboratory automation, and biosensors are also discussed.
更多
查看译文
关键词
sample preparation,point-of-care (POC),medical diagnosis,point-of-care testing (POCT),high-throughput screening,extraction,separations,microfluidics,biosensors
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要