The β-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness

Lindsay T. Michalovicz,Kimberly A. Kelly,Diane B. Miller,Kimberly Sullivan,James P. O'Callaghan

Life Sciences（2021）

引用 7|浏览20

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摘要

•Intermittent re-exposure to corticosterone primes neuroinflammation in a GWI model.•GWI-relevant chemical exposure primes neuroinflammatory responses beyond stress alone.•Propranolol reduces neuroinflammation in our long-term GWI model.

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关键词

CORT,DFP,GAPDH,GWI,LIF,LPS,OSM,PIC

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