High Inter- and Intratumoral Variability of Ki67 Labeling Index in Newly Diagnosed Prostate Cancer with High Gleason Scores.

Tatjana Vlajnic, Patrik Brunner,Serenella Eppenberger-Castori,Cyrill A Rentsch,Tobias Zellweger,Lukas Bubendorf

Pathobiology : journal of immunopathology, molecular and cellular biology（2022）

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摘要

Our data demonstrate major inter- and intratumoral variability of Ki67 LI in high-grade PC with a surprisingly low Ki67 LI in a subset of cases. Further studies are necessary to explore the molecular basis and potential clinical implications of a paradoxically low proliferation rate in high-grade PC.

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关键词

Ki67,Proliferation,Prostate cancer

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