6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1 / FAF1 complex dissociation-mediated autophagy

Jing Luo,Jialei Chen,Changhong Yang,Junyi Tan,Jing Zhao,Ning Jiang,Yong Zhao

International Immunopharmacology（2021）

引用 32|浏览11

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摘要

•6-Gingerol exerts neuroprotective effects against cerebral I/R injury.•6-Gingerol alleviates NLRP3 inflammasome and apoptosis via autophagy.•6-Gingerol exerts protective effects via TRPV1/FAF1 dissociation-mediated autophagy

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关键词

Cerebral I/R injury,6-Gingerol,NLRP3 inflammasome,Autophagy,Apoptosis,TRPV1/FAF1 signaling

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