Alternative platelet activation pathways and their role in neurodegenerative diseases

Neurobiology of Disease（2021）

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摘要

•Platelet functions go beyond hemostasis and wound healing.•Alternative platelet activation pathways are associated with brain function.•In Alzheimer's disease, increased amyloid-beta peptides promote platelet activation.•In Parkinson's disease, increased platelet α-syn leads to mitochondrial dysfunction.

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关键词

Platelets,Neurodegenerative diseases,Alternative platelet activation,Alzheimer's disease,Beta-amyloid,Parkinson's disease

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