Promoted antitumor therapy on pancreatic cancer by a novel recombinant human albumin-bound miriplatin nanoparticle

Dan Wang,Wenkai Feng, Xiaowei Wang,Dongfang Lin,Xuelei Wang,Xiaoru Guo,Qingfang Miao,Jie Ma,Guimin Xia

European Journal of Pharmaceutical Sciences（2021）

引用 3|浏览17

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摘要

•A novel recombinant human albumin-bound miriplatin nanoparticle (rHSA-miPt) was designed and formulated.•The rHSA-miPt could target tumor tissues.•The rHSA-miPt showed superior anti-tumor efficacy against pancreatic cancer and low toxicity in a xenograft tumor model .

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关键词

Miriplatin,Recombinant human serum albumin,rHSA-miPt,Pancreatic cancer,Nanoparticles

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