Children With Familial Hypercholesterolemia Display Changes In Ldl And Hdl Function: A Cross-Sectional Study

Jacob J Christensen,Ingunn Narverud,Maija Ruuth,Martin Heier,Matti Jauhiainen,Stine M Ulven,Martin P Bogsrud,Petri T Kovanen,Bente Halvorsen,Michael N Oda,Cecilie Wium,Kjetil Retterstøl,Katariina Öörni,Kirsten B Holven

ATHEROSCLEROSIS（2021）

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摘要

FH children displayed increased atherogenicity of LDL and disrupted HDL function. These newly observed functional alterations in LDL and HDL adds further understanding of the risk for atherosclerotic cardiovascular disease in FH children. This article is protected by copyright. All rights reserved.

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关键词

ASCVD,HDL-apoA-I exchange,LDL aggregation,Lipoproteins,NMR,children,cholesterol,familial hypercholesterolemia,metabolomics,reverse cholesterol transport

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