A pilot study of prehospital antibiotics for severe sepsis
ACADEMIC EMERGENCY MEDICINE(2022)
摘要
Severe forms of sepsis are major contributors to morbidity and mortality worldwide, with mortality rates as high as 25-60%. Sepsis with hypotension, and septic shock, which we define as sepsis with a systolic blood pressure = 90 mmHg that is refractory to an initial fluid bolus, are important subsets of sepsis and are medical emergencies for which timeliness of care is crucial. The literature demonstrates that early administration of antibiotics provides a significant mortality benefit in both conditions.
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