Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK

Frontal fibrosing alopecia (FFA) is a variant of lichen planopilaris (LPP) characterised primarily by inflammation and irreversible hair loss affecting the frontotemporal scalp. Expert consensus now suggests that FFA incidence is increasing and this has led to increased interest in its aetiopathogenesis. As FFA disproportionately affects post-menopausal women, our group previously assessed genotype-phenotype correlation in FFA, phenotyping a large female FFA cohort and demonstrating a causal role for genetic variants implicated in xenobiotic metabolism and antigen presentation.