Immunomodulation—A Molecular Solution to Treating Patients with Severe Bladder Pain Syndrome?

Björn Wullt,Daniel S C Butler,Ines Ambite, Julia Kinsolving,Christian Krintel,Catharina Svanborg

European Urology Open Science（2021）

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摘要

Interleukin-1 (IL-1) receptor antagonist immunotherapy is proposed as a new approach to treating bladder pain syndrome, a debilitating disorder. Treated patients experienced symptom relief and increased quality of life. Reduced neuroinflammation and IL-1 signaling provided molecular evidence of the treatment effects.

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关键词

Bladder pain syndrome,Interstitial cystitis,Immunotherapy,Interleukin-1 receptor antagonist

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