Sustained Inflation Versus Intermittent Positive Pressure Ventilation for Preterm Infants at Birth: Respiratory Function and Vital Sign Measurements

Expiratory tidal volumes of SI and IPPV inflations administered in the SAIL trial were highly variable in both treatment arms. Vital sign values were similar between groups throughout resuscitation. SI as operationalized in the SAIL trial was not superior to IPPV to promote lung aeration after birth in this study subgroup.