Butyrate functions in concert with myeloid-derived suppressor cells recruited by CCR9 to alleviate DSS-induced murine colitis

Tengfei Xiao,Ping Zhang,Tongbao Feng,Kefeng Lu,Xiaoyan Wang,Siyuan Zhou, Yetao Qiang

International Immunopharmacology（2021）

引用 8|浏览5

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摘要

•Butyrate alleviated DSS-induced murine colitis.•Butyrate functioned in concert with MDSCs to alleviate DSS-induced colitis.•The aggregation and migration of MDSCs depended on the recruitment of CCR9.•ALDH participated in the recruitment of MDSCs by CCR9.

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关键词

Butyrate,Short-chain fatty acid,Myeloid-derived suppressor cells,CCR9,Ulcerative colitis

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