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Non-neutralizing SARS CoV-2 directed polyclonal antibodies demonstrate cross-reactivity with the HA glycans of influenza virus

Praveenkumar Murugavelu,Reshma Perween,Tripti Shrivastava,Vanshika Singh,Hilal Ahmad Parray,Swarandeep Singh,Adarsh Kumar Chiranjivi,Ramachandran Thiruvengadam,Savita Singh,Naveen Yadav,Kamini Jakhar,Sudipta Sonar,Shailendra Mani,Sankar Bhattacharyya,Chandresh Sharma,Preeti Vishwakarma,Ritika Khatri,Anil Kumar Panchal,Supratik Das,Shubbir Ahmed,Sweety Samal,Pallavi Kshetrapal,Shinjini Bhatnagar,Kalpana Luthra,Rajesh Kumar

International Immunopharmacology（2021）

引用 15|浏览7
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摘要
•Cross talk between SARS-CoV-2 and Influenza.•HA immunized mice sera poorly or do not cross-react with the RBD of SARS-CoV2.•Cross reactive antibodies in SARS-CoV2 infection are non-neutralizing.
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关键词
SARS-CoV2,Influenza,Cross-reactivity,HIV-1,Glycan dependent,Neutralizing antibodies
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