Effects of Gynostemma pentaphyllum on spinal cord motor neurons and microglial cells in vitro

Gerburg Keilhoff, Christina Ludwig,Josephine Pinkernelle,Benjamin Lucas

Acta Histochemica（2021）

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摘要

•In organotypic cultures, GP was neuroprotective.•In organotypic cultures, GP activated astro- and microgliad.•In NSC-34 cells, high-dosed GP had degenerative/anti-proliferative effects.•In NSC-34 cells, GP supported the neuro-differentiation ability.•In BV-2 cells, GP activated nanoparticle uptake and migration ability.

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关键词

BV-2 cells,iNOS,Neuritogenesis,NSC-34 cells,Organotypic spinal cord culture,PPARγ

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