Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization

Idy H.T. Ho, Lhotse H.L. Ng, Xiaojie Cheng,Tony Gin,Chee Sam Chan,Wuping Sun,Lizu Xiao,Lin Zhang,Matthew T.V. Chan,William K.K. Wu,Xiaodong Liu

Neurobiology of Pain（2021）

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摘要

•ANXA2 is a novel MOR1-interacting protein regulating MOR1 sub-cellular localization.•ANXA2 retains MOR1 in late recycling endosomes after remifentanil exposure.

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关键词

ANXA2,MOR1,Remifentanil,MOR1 internalization

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