Correlation of manual semi-quantitative and automated quantitative Ki-67 proliferative index with OncotypeDXTM recurrence score in invasive breast carcinoma.

Brian S Finkelman,Amanda Meindl,Carissa LaBoy,Brannan Griffin,Suguna Narayan, Ryan Brancamp,Kalliopi P Siziopikou,Jennifer L Pincus,Luis Z Blanco

Breast disease（2021）

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摘要

These results highlight the limits of Ki-67 algorithms that use manual "hot spot" selection. Due to suboptimal concordance, Ki-67 is likely most useful as a complement to, rather than a surrogate for ORS, regardless of scoring method.

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关键词

Breast carcinoma,Ki-67,OncotypeDX,digital image analysis

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