Use of guanidine thiocyanate-based nucleic acid extraction buffers to inactivate poliovirus in potentially infectious materials

Michelle J E Honeywood,Stacey Jeffries-Miles,Kimberly Wong,Chelsea Harrington,Cara C Burns,M Steven Oberste,Michael D Bowen,Everardo Vega

Journal of Virological Methods（2021）

引用 5|浏览6

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摘要

•Nucleic acid extraction buffers inactivated poliovirus isolates and stool suspensions.•Ethanol enhanced inactivation by extraction buffers.•Complete inactivation was confirmed by blind passage.•Inactivation using extraction buffers will be useful for virus containment.

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关键词

Poliovirus,Virus inactivation,Nucleic acid extraction,Containment

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