Major Depressive Disorder Enhances Th2 and Th17 Cytokines in Patients Suffering from Allergic Rhinitis and Asthma.

Hugo A A Oyamada,Marcos Octávio S D Cafasso, Carolina M Vollmer,Fabianna Alvim,Lana M Lopes,Camilla Castro,Priscila M Sacramento,Marisa C Sales,Taissa M Kasahara,Ulisses C Linhares,Cleonice A M Bento

International archives of allergy and immunology（2021）

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摘要

Our findings suggest that not only the occurrence of MDD but also the severity of anxiety symptoms, may adversely affect the outcome of allergic reactions by favoring the production of cytokines implicated in the pathogenesis of AR and AA, a phenomenon that was attenuated by serotonin.

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Allergy,Major depressive disorder,Serotonin,Th17 cells,Th2 cells

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