Perioperative dual antiplatelet therapy for patients undergoing spine surgery soon after drug eluting stent placement.
Surgical neurology international(2021)
摘要
The treatment of patients requiring urgent or emergent spinal surgery within 6 months of undergoing a PCI for DES placement is challenging. As early interruption of DAPT may have catastrophic consequences, we hereby proposed a novel protocol involving stopping clopidogrel 5 days before and aspirin 3 days before spinal surgery, and bridging the interval with a reversible P2Y12 inhibitor until surgery. Moreover, postoperatively, aspirin could be started on postoperative day 1 and clopidogrel on day 2. Nevertheless, this treatment strategy may not be appropriate for all patients, and multidisciplinary approval of perioperative antiplatelet therapy management protocols is essential.
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关键词
Cangrelor,Drug-eluting stent,Dual antiplatelet therapy,Emergent spine surgery,P2Y12 inhibitor
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