HSPA12A improves endothelial integrity to attenuate lung injury during endotoxemia through activating ERKs and Akt-dependent signaling

Yuan Dai,Jiali Liu,Xiaojin Zhang,Xinxu Min,Jun Wu,Shuya Du,Tingting Li,Li Liu,Zhengnian Ding

International Immunopharmacology（2021）

引用 6|浏览11

暂无评分

摘要

•Endothelial cell injury contributes to vascular dysfunction in ALI.•HSPA12A protects endothelial cell survival and endothelial barrier integrity.•HSPA12A activates ERKs or Akt-dependent signaling pathway in LPS-treated HUVEC.

查看译文

关键词

Endothelial barrier,Acute lung injury,HSPA12A,Endotoxemia,ERKs,Akt

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要