In Situ Metabolomics Expands the Spectrum of Renal Tumours Positive on 99mTc-sestamibi Single Photon Emission Computed Tomography/Computed Tomography Examination

Thomas Papathomas,Antonios Tzortzakakis,Na Sun,Franziska Erlmeier,Annette Feuchtinger,Kiril Trpkov,Alina Bazarova,Alexandros Arvanitis,Wanzhong Wang,Bela Bozoky,Georgia Kokaraki,Rimma Axelsson,Axel Walch

European Urology Open Science（2020）

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摘要

Our study provides novel molecular insights into renal neoplasia, and supports the feasibility of integrated in situ metabolomic profiling for the diagnostics and classification of renal tumours. The results of this study suggest that renal tumours positive on 99mTc-sestamibi single photon emission computed tomography/computed tomography should be biopsied and analysed in an integrated fashion to inform clinical management.

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99mTc-sestamibi SPECT/CT,Renal tumour/in situ metabolomics

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