Cardiac Contractility Modulation in Patients with Ischemic versus Non-ischemic Cardiomyopathy: Results from the MAINTAINED Observational Study

•Under CCM therapy, patients with NICM have more pronounced improvement in LVEF and TAPSE than patients with ICM in the long term.•Patients with more severely impaired LVEF of 20 to 25% also benefit from CCM therapy.•Safety events related to the device are rare with this therapy.