APE1/Ref-1 as a Novel Target for Retinal Diseases.

Curtis Heisel,Jonah Yousif, Mahmut Mijiti, Kostas Charizanis, Mitchel Brigell,Timothy W Corson,Mark R Kelley

Journal of cellular signaling（2021）

引用 9|浏览4

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摘要

APE1/Ref-1 (also called Ref-1) has been extensively studied for its role in DNA repair and reduction-oxidation (redox) signaling. The review titled: " The multifunctional APE1 DNA repair-redox signaling protein as a drug target in human disease"

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关键词

APE1/Ref-1,Angiogenesis,Apurinic/apyrimidinic endonuclease,Choroid,Inflammation,Neovascularization,Ocular clinical trial,Redox effector factor 1,Redox signaling,Retina,Transcription factors

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