Frequency Of Subclinical Hypothyroidism In Old-Age Population

Khalil Ullah Shabir, Kashif Ullah Shabir, Maria Qadri,Uzair Yaqoob, Syed Muhammad Ahsan Nawaz, Balvender Singh

JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN(2021)

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摘要
This study was conducted to determine the frequency of subclinical hypothyroidism (SCH) in the old age population (> 60 years). A cross-sectional study was conducted from July 2019 to January 2020 at Jinnah Postgraduate Medical Centre, Karachi, Pakistan. Healthy subjects (having no active complaint) of either sex aged 60-80 years were included. Those already on thyroid replacement, preexisting thyroid diseases, prior radiation therapy, or having chronic kidney disease were excluded. A total of 133 participants, 79 males and 54 females, were selected with a mean age of 69.5 +/- 6.4 years. There were 29 diabetics, 30 hypertensives, and 10 smokers. A total of 17 (12.8%) were found to have SCH. On stratification, gender, diabetes mellitus, and hypertension had a significant association with the presence of SCH. SCH is a modifiable risk factor, more in females, diabetics, hypertensives, and the old age population. These results highlight the need for screening for SCH in primary care settings, especially in old age.
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关键词
Subclinical hypothyroidism, Old age, Gender, Diabetes, Hypertension
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