Efficacy and adverse events of selective serotonin noradrenaline reuptake inhibitors in the management of postoperative pain: A systematic review and meta-analysis

Alexander Schnabel,Stephanie Weibel,Sylvia U. Reichl,Michael Meißner,Peter Kranke,Peter K. Zahn,Esther M. Pogatzki-Zahn,Christine H. Meyer-Frießem

Journal of Clinical Anesthesia（2021）

引用 9|浏览5

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摘要

•Perioperative duloxetine might reduce postoperative pain after 24 and 48 h, but not after 2 h.•Perioperative duloxetine may reduce the risk of CPSP 6 months after surgery.•However, duloxetine increases the risk of dizziness.

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关键词

Meta-analysis,Postoperative pain,Selective serotonin noradrenaline reuptake inhibitors,Duloxetine

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