The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders

Neuroscience & Biobehavioral Reviews(2021)

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摘要
•Autism and related disorders display an overlap in presentation and neuropathology.•Impaired synaptic, metabolic, proliferation, apoptosis and immune pathways are repeatedly implicated.•Dysregulated non-coding RNAs and aberrant epigenetic profiles are consistently reported.•Strong evidence for GABAergic, glutamatergic and glial dysfunction is provided.•The cerebellum and frontal cortex are most consistently implicated.
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关键词
Autism,Autism Spectrum Disorder (ASD),Post-mortem studies,Systematic review
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