Opportunities, barriers, and recommendations in down syndrome research.

James A Hendrix,Angelika Amon,Leonard Abbeduto,Stamatis Agiovlasitis,Tarek Alsaied,Heather A Anderson,Lisa J Bain,Nicole Baumer,Anita Bhattacharyya,Dusan Bogunovic,Kelly N Botteron,George Capone,Priya Chandan, Isabelle Chase,Brian Chicoine,Cécile Cieuta-Walti,Lara R DeRuisseau,Sophie Durand,Anna Esbensen,Juan Fortea,Sandra Giménez,Ann-Charlotte Granholm, Laura J Hahn,Elizabeth Head,Hampus Hillerstrom,Lisa M Jacola,Matthew P Janicki,Joan M Jasien,Angela R Kamer,Raymond D Kent,Bernard Khor,Jeanne B Lawrence, Catherine Lemonnier,Amy Feldman Lewanda,William Mobley,Paul E Moore, Linda Pollak Nelson,Nicolas M Oreskovic,Ricardo S Osorio,David Patterson,Sonja A Rasmussen,Roger H Reeves,Nancy Roizen,Stephanie Santoro,Stephanie L Sherman,Nasreen Talib,Ignacio E Tapia,Kyle M Walsh,Steven F Warren,A Nicole White,Guang William Wong,John S Yi

Translational science of rare diseases（2021）

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摘要

This review highlights many of the scientific gaps that exist in DS research. Based on these gaps, a multidisciplinary group of DS experts has made recommendations to advance DS research. This paper may also aid policymakers and the DS community to build a comprehensive national DS research strategy.

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关键词

Alzheimer’s disease,Down syndrome,autism spectrum disorder,autoimmune disease,cognitive development,congenital heart disease,intellectual disability,leukemia,muscle hypotonia,obesity,obstructive sleep apnea,periodontitis

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