Respective roles of Glycoprotein VI and FcγRIIA in the regulation of αIIbβ3-mediated platelet activation to fibrinogen, thrombus buildup, and stability.

Muhammad Usman Ahmed,Nicolas Receveur,Emily Janus-Bell,Clarisse Mouriaux,Christian Gachet,Martine Jandrot-Perrus,Béatrice Hechler,Elizabeth E Gardiner,Pierre H Mangin

Research and practice in thrombosis and haemostasis（2021）

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摘要

This study provides evidence that GPVI, but not FcγRIIA, induces platelet activation and spreading on fibrinogen, and promotes thrombus buildup and stability.

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