Spatial and temporal analysis of invasive pneumococcal disease due to erythromycinresistant serotypes.

Abelardo Claudio Fernández Chávez,Luis García Comas,Diana Gómez Barroso,Rebeca Ramis Prieto,Nieves López Fresneña,Cornelia Bishofberguer Valdes,Jesús María Aranaz Andrés

Enfermedades infecciosas y microbiologia clinica（2021）

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摘要

The decrease in IPD due to resistant STPCV13 was associated with an increase in childhood vaccination coverage. The presence of clusters due to STnoPCV13 after the date of inclusion of the 13-valent vaccine in the childhood vaccination calendar indicates serotypes replacement. The increase in cases of resistant STnoPCV13 could be related to the replacement of vaccine serotypes in nasopharyngeal colonization, facilitated by the consumption of macrolides still at high levels in MC.

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关键词

Antibiotic resistance,Consumo de antibióticos,Enfermedad neumocócica invasiva,Invasive pneumococcal disease,Resistencia antibiótica,Use of antibiotics

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