Procalcitonin As A Biomarker For Ventilator Associated Pneumonia In Covid-19 Patients: Is It An Useful Stewardship Tool?

Marina Farrel Côrtes,Bianca Leal de Almeida,Evelyn Patricia Sanchez Espinoza,Aléia Faustina Campos,Maria Luiza do Nascimento Moura,Matias C Salomão,Icaro Boszczowski,Maristela Pinheiro Freire,Laina Bubach de Carvalho,Gláucia Paranhos-Baccalà,Silvia Figueiredo Costa,Thaís Guimarães

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE（2021）

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摘要

Ventilator associated pneumonia(VAP) is a severe complication that can lead to high mortality when not early identified or when therapy is delayed. The aim of this study was to evaluate procalcitonin(PCT) as a biomarker for VAP development. In total, 73 hospitalized patients with COVID-19 were analyzed. PCT levels greater than 0.975ng/mL were more related to VAP. No association was found for C-reactive protein (CRP). The results show that procalcitonin may be a pertinent biomarker for VAP diagnosis and can be a helpful tool for antibiotic withdrawal. (c) 2021 Elsevier Inc. All rights reserved.

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关键词

COVID-19, Procalcitonin, Ventilator Associated Pneumonia, Secondary infection, SARS-Cov-2 pandemic

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