Senkyunolide I protect against lung injury via inhibiting formation of neutrophil extracellular trap in a murine model of cecal ligation and puncture

International Immunopharmacology(2021)

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摘要
•Senkyunolide I protects against lung injury induced by sepsis.•Senkyunolide I reduces inflammatory and oxidative responses in the lungs of septic mice.•Senkyunolide I inhibits neutrophil extracellular trap formation in the lungs of septic mice.•Senkyunolide I inhibits neutrophil extracellular trap released by neutrophils.
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关键词
Sepsis,Acute lung injury,Senkyunolide I,Neutrophil extracellular trap
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