VCAM-1 as a predictor biomarker in cardiovascular disease

Mayarling Francisca Troncoso,Jafet Ortiz-Quintero,Valeria Garrido-Moreno,Fernanda Sanhueza-Olivares,Alejandra Guerrero-Moncayo,Mario Chiong,Pablo F. Castro,Lorena García,Luigi Gabrielli,Ramón Corbalán,Luis Garrido-Olivares,Sergio Lavandero

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease（2021）

引用 56|浏览10

暂无评分

摘要

The vascular cellular adhesion molecule-1 (VCAM-1) is a protein that canonically participates in the adhesion and transmigration of leukocytes to the interstitium during inflammation. VCAM-1 expression, together with soluble VCAM-1 (sVCAM-1) induced by the shedding of VCAM-1 by metalloproteinases, have been proposed as biomarkers in immunological diseases, cancer, autoimmune myocarditis, and as predictors of mortality and morbidity in patients with chronic heart failure (HF), endothelial injury in patients with coronary artery disease, and arrhythmias. This revision aims to discuss the role of sVCAM-1 as a biomarker to predict the occurrence, development, and preservation of cardiovascular disease.

查看译文

关键词

ACE2,ADAMs,ADAM-17,AF,AGEs,Ang II,Ang-(1–7),BMCs,BNP,CABG,CCL+,CD+,CD106,cIAP1/2,CRP,cTnT-hs,CVD,DCAL,ERK,ERM,ET-1,GDF15,HF,HFPEF,HFrEF,HUVEC,Ig,IκB,IKK,LVEF,LPS,MCAO,NO,NT-proBNP,P2X7,PFKFB3,POAF,RGC32,TACE,TIMP-3,RIP1,sADAM8,sVCAM-1,TAK1,TNFR1,TRAF2,VCAM-1,VLA-4,ZDF

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要