MRI Compatibility Measurements of SIAT aPET

1130 Introduction: Dual-modality small animal PET/MRI imaging is a very powerful tool in biomedical research. A MRI compatible small animal PET scanner called SIAT aPET was developed by using dual-ended readout depth encoding detectors to simultaneously achieve a uniform high spatial resolution and high sensitivity at Shenzhen Institutes of Advanced Technology (SIAT). In this work, the mutual interference is measured and simultaneous PET/MRI imaging is performed by inserting the SIAT aPET into the uMR790 3T MRI scanner of United Imaging. Methods: SIAT aPET consists of 4 detector rings with 12 detector modules per ring. The detector module consists of one 23×23 LYSO array with crystals of 1.0×1.0×20.0 mm3, read out by two 8×8 SiPM arrays from both ends. The SiPM array is the Hamamatsu S13361-3050NE-08 array with a pixel size of 3.0×3.0 mm2 and a pitch of 3.2 mm. The detector ring diameter of the scanner is 111 mm and the axial field of view is 106 mm. It achieves a spatial resolution of Conclusions: SIAT aPET, a high spatial resolution, high sensitivity and MRI compatible small animal PET insert, was developed by using dual-ended readout depth encoding detectors. The mutual interference of the SIAT aPET and the uMR790 3T MRI scanner were measured. The results showed that the MRI imaging had negligible effect on the PET performance and the PET scanner had accepted effect on the MRI imaging. The SIAT aPET can be successfully inserted into MRI scanners for simultaneously PET/MRI studies of small animals such as mice, rats and marmosets. Acknowledgments: This work is supported by the Scientific Instrument Innovation Team of CAS (GJJSTD20180002), the Hundred-Talent Program of the CAS (Yongfeng Yang) and the Key Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong Province.