SARS-CoV-2 vaccine effectiveness trumps immunogenicity in solid organ transplant recipients

On June 8 , Malinis et al, published their preliminary observations of the SARS-CoV-2 vaccine effectiveness in solid organ transplant recipients (SOTR) in the AJT (1). Their timely, real world results based on current practices are reassuring. Several studies have now shown 100% effectiveness of multiple SARS-CoV-2 vaccines in preventing hospitalization and death. As of May 17 , 2021, 860 of 123 million (0.0008%) who were fully vaccinated developed breakthrough infections that required hospitalization or were fatal.