β-patchoulene protects against non-alcoholic steatohepatitis via interrupting the vicious circle among oxidative stress, histanoxia and lipid accumulation in rats

•β-patchoulene protects against high-fat diet induced non-alcoholic steatohepatitis.•β-patchoulene alleviates inflammation via inhibiting the activation of NLRP3.•β-patchoulene inhibits hepatic oxidative stress, histanoxia and lipid accumulation.•sCD36 may be a promising non-invasive diagnostic method for NASH.