Efficient C•G-to-G•C Base Editors Developed Using CRISPRi Screens, Target-Library Analysis, and Machine Learning

Luke W. Koblan,Mandana Arbab,Max W. Shen,Jeffrey A. Hussmann,Andrew V. Anzalone,Jordan L. Doman,Gregory A. Newby,Dian Yang,Beverly Mok,Joseph M. Replogle,Albert Xu,Tyler A. Sisley,Jonathan S. Weissman,Britt Adamson,David R. Liu

Nature Biotechnology（2023）

Cited 135|Views129

Key words

Genetic engineering,Targeted gene repair,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics

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