Serum neurofilament light chain levels in healthy individuals: A proposal of cut-off values for use in multiple sclerosis clinical practice

Paola Valentino,Fabiana Marnetto,Serena Martire,Simona Malucchi,Cecilia Irene Bava,Maja Popovic,Antonio Bertolotto

Multiple Sclerosis and Related Disorders（2021）

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摘要

•sNFL values in healthy controls are stable in short term follow up.•Age-dependent cut-off values were defined based on healthy controls.•Cut-offs can be used to interpret sNFL levels in MS patients.

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关键词

Multiple sclerosis,Neurofilament light chain,NFL,Serum,Reference values,Biomarker,Variability

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