Spleen emptying does not correlate with faster oxygen kinetics during a step-transition supine cycling
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM(2021)
摘要
This manuscript quantified spleen volume changes and examined the relationship between those changes and oxygen uptake kinetics during supine cycling. Ten volunteers (age = 22 +/- 3), completed 3 step transitions from 20 W to their power output at 90% gas exchange threshold. Ultrasonic measurements of the spleen were performed each minute. The largest spleen volume reduction was 105 mL (p = 0.001). No associations existed between i) spleen volumes at rest; and ii) spleen volume changes (%) and tau pulmonary oxygen uptake (tau<(V) over dot>O-2p). Larger resting spleen volume and greater emptying do not correlate with a faster tau<(V) over dot>O-2p. Novelty: Greater splenic contractions do not augment tau<(V) over dot>O-2p, irrespective of spleen emptying and subsequent erythrocyte release.
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关键词
spleen contraction, oxygen transport, ultrasonic imaging
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