Cotranslational Targeting and Posttranslational Translocation can Cooperate in Spc3 Topogenesis

Sung-Jun Jung,Ji Eun Hani Kim,Tina Junne,Martin Spiess,Hyun Kim

Journal of Molecular Biology（2021）

引用 2|浏览2

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摘要

•The head-on insertion of Spc3 occurs independently of the Sec62/Sec63 complex.•Sec62 recognizes the head-on inserted Spc3 variant.•The Sec62/Sec63 complex mediates reorientation of the head-on inserted Spc3.

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关键词

membrane protein,Sec61,Sec62,topology,yeast

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