An integrative analysis of genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA detects noninvasive diagnostic markers for gliomas.

Neuro-oncology advances(2021)

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摘要
The 5hmC-Seal in cfDNA offers the promise as a noninvasive approach for effective detection of gliomas in a screening program.
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关键词
5-hydroxymethylcytosine,biomarker,cell-free DNA,diagnosis,glioma
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