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Discovery of Arylsulfonamide Nav1.7 Inhibitors: IVIVC, MPO Methods, and Optimization of Selectivity Profile.

Anthony Roecker,Mark Layton,Michael Kelly,Joseph Pero,Thomas Greshock, Ting Zhang,Richard Kraus,Yuxing Li,Christopher Daley,Aneta Jovanovska, Becky Klein,Michelle Clements,Jixin Wang,Darrell Henze,Geoffrey Varty,Jeanine Ballard,Deping Wang,Fuqiang Zhao, Christopher Regan,Hillary Regan,Leo Joyce,Edward Sherer, Christopher John,Xuanjia Peng,Xiu Wang,Haiyan Sun,Andrea Houghton,Christopher Burgey

ACS Medicinal Chemistry Letters（2021）

Cited 9|Views29
Key words
Na(v)1.7,Na(v)1.6,ion channel,pain,arylsulfonamide,selectivity,olfaction
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