Giant versus regular parathyroid adenoma: A retrospective comparative study

•Our sample included a high percentage of giant PTA compared to the literature. This might reflect a delay in diagnosis.•Despite the difference in size, both giant and regular adenomas seem to run a similar clinical course, and the success of surgical treatment was found to be comparable.•Biochemical abnormalities in PTH levels could have a potential role in predicting the weight and size of PTA.