Dose-intensified Versus Conventional-dose Salvage Radiotherapy for Biochemically Recurrent Prostate Cancer After Prostatectomy: The SAKK 09/10 Randomized Phase 3 Trial

Dose-intensified salvage radiotherapy after radical prostatectomy did not show superior outcomes for freedom from biochemical progression when compared to conventional-dose treatment. However, the higher dose was associated with a higher rate of late gastrointestinal toxicity.